Profile
Prof. Wu Li received his Ph.D. degree in 2015 from Wuhan University under the supervision of Prof. Aiwen Lei. In 2016‒2021, he worked as a postdoctoral researcher with Prof. Matthias Beller in Leibniz Institute for Catalysis in Rostock (LIKAT Rostock, Germany). In 2022, he got a professor position in College of Chemistry and Molecular Sciences (CCMS) of Wuhan University. His current research interest is Catalytic Deuterium Labeling.
Professional Experience:
2022.02-present: Professor, College of Chemistry and Molecular Sciences, Wuhan University
2016.3-2021.12: LIKAT, Rostock, Germany---Postdoc with Prof. Dr. Matthias Beller
Education:
2012.9-2015.6: Wuhan University, China---Ph.D. Degree of Organic Chemistry, with Prof. Dr. Aiwen Lei
2009.9-2012.6: Nanjing Normal University, China---M.S. Degree of Organic Chemistry with Prof. Dr. Peipei Sun.
Research Activities:
Deuterium labelling chemistry
Nanocatalysis
Eletrocatalysis
Synthetic chemistry
Organic synthesis
Publications in last five years:
1. Bu, F.#, Deng, Y.#, Xu, J., Yang, D., Li, Y., Li, W.* and Lei, A.*, Electrocatalytic reductive deuteration of arenes and heteroarenes. Nature 2024, 634, 592–599.
2. He, M#, Deng, X.#, Yao. F#, Wang. Y, Gao, Y, Wang, P., Wan, Q., Chen, K., Wang, L., Yi, H., Zhang, H.*, Li, W.* and and Lei, A.*, Boron Cluster as Efficient Shipper for Electrocatalytic Radical H/D Exchange, Nat. Catal. 2025, 8, 784–793.
3. Qiu, F., Yang, L., Wang, Y., Gao, Y., Chen, Y., Lei, A.* and Li, W.*, Nickel-Catalyzed Deuteration of Benzylic C(sp3)–H Bonds using D2O, Nat. Synth. 2025, 4, 1141–1150.
4. Bu, F., Qiu, F., Gao, Y., Deng, Y., Lei, A., and Li, W.*, Heterogeneous catalytic deuteration using D2O and advances in the application of deuterium labelling. Chem. Soc. Rev. 2026, 55, 3645–3686.
5. Bu, F.#, Deng, Y.#, Lu, L.#, Li. Y., Song, W., Yang, Z., Luo, X., Dong, X., Yi, R., Wang, S., Lei, A.*, and Li, W.*, Electrocatalytic Alkene Hydrogenation/Deuteration, J. Am. Chem. Soc. 2025, 147, 5785−5795.
6. Bu, F.#, Deng, Y.#, Shi, P., Huang, R., Tan, J., Li, H., Chen, Y., Lei, A., and Li, W.*, Thiol-Regulated Rhodium Nanocatalyst for Electrochemical Reductive Perdeuteration of Alkenes J. Am. Chem. Soc. 2026, 148, 7322−7332.
7. Hu, J., Hu, J., Wang, Y., Zeng, C. Zhang, H. Wei, Z.*, Li, W.*, Yi, H.* and Lei, A.*, Parallel paired electrolysis of industrial exhaust SO2 and diols for value-added sulfite esters synthesis, Nat. Synth. 2026, 5, 629–637.
8. Li, Y.#, Peng, Y.#, Dong, W.#, Jiang, X., Lu, L., Yang, D., Hsu, L-C., Li, W.*, Su, B-L.* and Lei, A.*, May 2024, Multiscale Anion-Hybrid in Atomic Ni Sites for High-Rate Water Electrolysis: Insights into the Charge Accumulation Mechanism, J. Am. Chem. Soc. 2024, 146, 14194–14202.
9. Li, H.#, Li, Y.#, Chen, J., Lu, L., Wang, P., Hu, J., Ma, R., Gao, Y., Yi, H.*, Li, W.* and Lei, A.*, Scalable and Selective Electrochemical Hydrogenation of Polycyclic Arenes, Angew. Chem. Int. Ed. 2024,
63, e202407392.
10. Li, Y., Lu, L., Jiang, X., Yang, D, Chen, J-L., Chowdhury, A. D., Li, W.*, Pei, X.*, and Lei, A.*, Dynamic Boron-doping Switched Chitin-based Single-site Pt Catalyst for Chemo-selective Hydrogenation, Nat. Commun. 2025, 16, 2296.
11. Wang, X.#, Li, Y.#, Wang, M., Gao, Y., Ma, Z., Lei, A.* and Li, W.*, Nickel nanoparticles catalyzed hydrogenation and deuteration for a general amine synthesis, Chin. J. Catal. 2025, 72, 392−401.
12. Qiu, F. #, Chen, Y.#, Liao, P., Gao, Y., Guo, M.*, Zhang, H.*, Lei, A.* and Li, W.*, Electrochemical selective deuterium labelling of N-heteroarenes, Green Synth. Catal. 2025, 6, 439-443.
13. Li, H., Shabbir, M., Li, W.* and Lei, A.*, Recent Advances in Deuteration Reactions, Chin. J. Chem. 2024, 42, 1145–1156.
14. Qiu, F., Yang, L., Gao, Y., Yang, J., Lei, A.* and Li, W.*, Selective and Scalable Deuteration of Heteroarenes Using Nickel-Based Nanoparticles, Chin. J. Chem. 2024, 42, 2993–2998.
15. Yang, L.#, Qiu, F.#, Chen, Y., Gao, Y., Wang, T.*, Lei, A.* and Li, W.*, Copper-Catalyzed Deuteration of (Hetero)Aryl Halides, Green Synth. Catal. 2024, https://doi.org/10.1016/j.gresc.2024.12.004.
16. Wang, Y.#, Qiu, F.#, Yao F., Zeng, L., Lei, A.* and Li, W.*, Ru-based nanoparticle catalyzed direct H/D exchange of silanes, Chem. Commun., 2025, 61, 6607–6610. (2025 Emerging Investigators)
17. Gao, Y.#, Li, Y.#, Su, Y., Wang, Y., Li, H., Wang, X., Li, P., Hu, J., Yi, H.*, Li, W.* and Lei, A.*, Perdeuteration of (Hetero)arenes in Flow Enabled by Defective Porous Carbon, Adv. Synth. Catal. 2025, 367, e70037.
18. Yao, F., Gao, Y., Wang, Y., Zeng, L., Lei, A. and Li, W.*, Electrochemical Deoxyarylation of Aromatic Aldehydes and Ketones, Org. Lett. 2025, 27, 4124−4128.
19. Li, W., Rabeah, J., Bourriquen, F., Yang, D., Kreyenschulte, C., Rockstroh, N., Lund, H., Bartling, S., Surkus, A-E., Junge, K., Brückner, A.*, Lei, A.*, and Beller, M.*, Scalable and selective deuteration of (hetero)arenes, Nature Chem., 2022, 14, 334–341 (Highlighted in “Synfacts”).