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易红 武汉大学高等研究院教授，国家高层次青年人才，博士生导师。迄今， 以（共同）通讯作者发表学术论文40余篇，包括 Nature Chemistry 1篇, Nature Synthesis 2篇, Chem 1篇, Natl. Sci. Rev. 1篇, J. Am. Chem. Soc. 6篇, Angew. Chem. Int. Ed. 5篇, Nat. Commun. 5篇。主持国家自然科学基金青年科学基金项目B类（原国家优秀青年基金），国家重点研发计划“催化专项”青年科学家项目、湖北省省级技术创新项目。

学习与工作简历

2008.09-2012.06在武汉大学化学分子科学学院化学基地班学习；

2017.6博士毕业于武汉大学化学与分子科学学院，师从雷爱文教授；

2017.9-2019.11作为洪堡学者博士后在德国柏林工业大学进行研究，合作导师Martin Oestreich教授；

2020.01-2021.11作为JSPS研究员在名古屋大学工作，合作导师Cathleen M. Crudden教授。

2022.03 - 2026.01 武汉大学高等研究院特聘研究员、博士生导师

    2026.02-至今          武汉大学高等研究院 教授、博士生导师

研究方向简介

聚焦复杂合成体系的原位谱学与反应机制研究，围绕均相合成反应中的关键科学问题，发展多种原位谱学表征方法，解析反应过程中活性物种的形成、演化与转化规律，揭示复杂反应体系的内在机制，为突破合成化学中的关键瓶颈、实现反应优化与绿色合成提供理论依据。主要研究方向：

（1）复杂体系原位谱学方法建立：开发并优化适用于复杂反应环境的原位谱学技术，结合光化学、电化学等研究手段，实现对反应过程的实时、动态监测与多维表征。

（2）活性中间体结构表征与反应机制：针对光/电合成反应中的关键活性中间体，如自由基、有机金属中间体和金属簇等，开展结构表征与动态追踪研究，阐明化学键活化、单电子转移及选择性转化等关键步骤的反应机制，并推动机制认识在反应优化和机理可视化中的应用。

（3）机理导向绿色合成反应开发：聚焦合成过程中的关键限速步骤与选择性控制因素，建立从机制解析到反应设计的研究路径，发展绿色、高效、选择性可控的合成转化新体系。

荣誉与奖励

徐元植顺磁共振波谱学优秀青年奖（2025）

湖北省“百人计划”创新人才（2024）

武汉市“武汉英才”优秀青年人才（2022）

日本学术振兴会研究员（2020）

德国洪堡基金会洪堡学者（2017）

代表性学术论文

1.       Pengjie Wang, Wei Ding, Shuang Deng, Zhiqiang Zhang, Xiaotian Qi,* Aiwen Lei,* and Hong Yi*. Deciphering Mechanistic Pathways and Selectivity in Electrochemical Oxidative C–N Bond Formation between Olefins and Sulfonamides. J. Am. Chem. Soc. 2026, 148, 10692–10701.

2.       Tianjiao Peng, Ziyue Chen, Xi Cui, Hanning Jiang, Yongyi Li, Zhenwei Wei,* Aiwen Lei,* and Hong Yi*. Paired Electrolysis Enables para-C–H Amination of Phenols with Nitroarenes and Mechanistic Visualization via Multifunctional Electrochemical Mass Spectrometry. Nat. Commun. 2026, 10.1038/s41467-026-70691-x.

3.       Demin Ren, Shuang Deng, Yatao Wang, Wei Ding, Pengjie Wang, Jia Yan, Shengchun Wang, Jiaxin Yuan, Baoquan Wan, Xiaotian Qi,* Aiwen Lei,* and Hong Yi*. Radical Defluoroallylation of Polyfluoroalkyl Compounds with Alkenes via Synergistic Photoredox/Cobalt Catalysis. Nat. Commun. 2026, 17, 2971.

4.       Jingcheng Hu, Jiayu Hu, Yatao Wang, Chen Zeng, Heng Zhang, Zhenwei Wei,* Wu Li,* Hong Yi,* and Aiwen Lei*. Parallel Paired Electrolysis of Industrial Exhaust SO2 and Diols for Value-Added Sulfite Esters Synthesis. Nat. Synth. 2026, 10.1038/s44160-025-00968-4.

5.       Shuxiang Zhu, Zhipeng Guan, Yanlong Liu, Heng Zhang,* Aiwen Lei,* and Hong Yi* Unveiling the Switchable Chemoselectivity Mechanism in Electrochemical Nickel-Catalyzed C(sp²)-O Coupling of Phenols and Aliphatic Alcohols J. Am. Chem. Soc. 2025, 147, 31603–31617.

6.            Haozhe Dong, Xuejie Wang, Pingsen Shi, Nian Chen, Zhiqiang Zhang, Jia Yan, Aiwen Lei* and Hong Yi* N-Heterocyclic Carbene-Ligated Mixed-valent Linear Cu₃ Cluster for Enhanced Electrocatalytic Nitrite Reduction. J. Am. Chem. Soc. 2025,147, 29423-29430.

7.            Shuxiang Zhu, Zhipeng Guan, Yanlong Liu, Heng Zhang,* Aiwen Lei,* and Hong Yi*. Electrochemical Amino‐Oxygenation Cyclization via Alkene Radical Cation/Bisnucleophile Engagement to Saturated N/O‐Heterocycles. Angew. Chem. Int. Ed. 2025, 64, e202501424.

8.           Demin RenYuan WangZhao LiuYatao WangWei DingFengze YaoXiaotian Qi* Aiwen Lei* Hong Yi* Cobaloxime-Catalyzed Radical Allylic C–H Sulfonylation Through Synergistic XAT/HAT Processes ACS Catal. 2025, 15, 13127–13135

9.            Shengchun Wang, Xu Luo, Yuan Wang, Zhao Liu, Yi Yu, Xuejie Wang, Demin Ren, Pengjie Wang, Yi-Hung Chen,* Xiaotian Qi,* Hong Yi,* and Aiwen Lei*. Radical-triggered translocation of C-C double bond and functional group. Nat. Chem. 2024, 16, 1621-1629.

10.       Jingcheng Hu, Haoyu He, Minghao Xu, Xiaotian Qi, Chao Fu, Hong Yi,* and Aiwen Lei*. Adduct-catalyzed tandem electro-thermal synthesis of organophosphorus (III) compounds from white phosphorus. Natl. Sci. Rev. 2025, 12, nwaf008.

11.       Lei Nie, Jiayi Yang, Zhao Liu, Shibo Zhou, Suming Chen, Xiaotian Qi, Aiwen Lei,* and Hong Yi*. Linear Paired Electrolysis Enables Redox-Neutral (3 + 2) Annulation of Benzofuran with Vinyldiazo Compounds, J. Am. Chem. Soc. 2024, 146, 31330-31338.

12.       Xing Liu, Jianxiong Chen, Zhenwei Wei,* Hong Yi,* and Aiwen Lei*. Deciphering reactive intermediates in electrooxidative coupling of indoles through real-time mass spectrometry. Chem. 2024, 10, 2131-2146.

13.       Xing Liu, Dali Yang, Zhao Liu, Yunkun Wang, Yichang Liu, Shengchun Wang, Pengjie Wang, Hengjiang Cong, Yi-Hung Chen,* Lijun Lu,* Xiaotian Qi,* Hong Yi,* and Aiwen Lei*. Unraveling the Structure and Reactivity Patterns of the Indole Radical Cation in Regioselective Electrochemical Oxidative Annulations. J. Am. Chem. Soc. 2023, 145, 3175-3186.

14.       Zhaoliang Yang, Wenyan Shi, Hesham Alhumade, Hong Yi,* and Aiwen Lei*. Electrochemical oxidative C(sp³)–H cross-coupling with hydrogen evolution. Nat. Synth. 2023, 2, 217-230.

15.       Kailun Liang, Dongmei Zhang, Yanming Su, Lijun Lu, Jun Hu, Yi-Hung Chen,* Xinxing Zhang,* Aiwen Lei,* and Hong Yi*. Fragile intermediate identification and reactivity elucidation in electrochemical oxidative alpha-C(sp³)-H functionalization of tertiary amines. Chem. Sci. 2023, 14, 4152-4157.