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朱泉霏，公共卫生学院特聘副研究员，硕士研究生导师。2017年于武汉大学化学与分子科学学院获得博士学位（分析化学专业）。2018年至2021年在武汉大学大学和澳门科技大学开展博士后研究。2022年任武汉大学公共卫生学院 特聘副研究员。 主要研究方向为环境卫生、代谢组学、环境污染物内暴露、色谱-质谱分析。近年来在Analytical Chemistry, Trends in Analytical Chemistry等期刊上发表SCI论文40余篇，其中以第一作者或共同通讯作者身份发表SCI论文19篇。获得国家自然科学青年基金、中国博士后科研基金，中国博士后基金委—“澳门青年学者”计划（第一届）资助，参与国家自然科学基金重点项目研究等。

研究方向

（1）环境污染物内暴露研究：

针对“环境内分泌干扰物（EDCs）暴露与健康的关系”这一重要科学问题，建立高效的污染物体内代谢示踪方法，实现EDCs的体内代谢示踪，探索生殖健康人群中EDCs暴露与代谢组之间的关系。

（2）基于衍生化的色谱质谱代谢组分析方法研究

开展了多种基于衍生化结合色谱质谱技术的代谢组学研究方法，构建亚代谢组学分析研究平台，应用于临床疾病生物标志物研究。

 主持项目

（1）2020/01-2022/12，基于质谱探针-液相色谱质谱联用技术的羟基脂肪酸支链脂肪酸酯全分析，基金号21904099，国家自然科学青年基金21万元，主持；

（2）2019/01-2020/12，基于质谱探针技术的肥胖模型鼠FAHFAs代谢物的分析方法研究，基金号2018M642893，第64届博士后科学基金；

（3）2020/02-2022/01，博士后国（境）外交流项目—“澳门青年学者计划（第一届）”；

（4）2022/01-2023/12，FAHFAs深度分析方法及应用研究，中央高校基本科研业务费专项资金（青年教师资助项目）

（5）“武汉英才（优秀青年人才）”，2023年

代谢性学术成果

1. Quan-Fei Zhu, Yan-Zhen Wang, Na An, Jun-Di Hao, Peng-Cheng Mei, Ya-Li Bai, Yu-Ning Hu, Pei-Rong Bai, Yu-Qi Feng*, Alternating Dual-Collision Energy Scanning Mass Spectrometry Approach: Discovery of Novel Microbial Bile-Acid Conjugates. Analytical Chemistry, 2022, 94, 2655-2664.

2. Quan-Fei Zhu, Na An, Yu-Qi Feng*, In-Depth Annotation Strategy of Saturated Hydroxy Fatty Acids Based on Their Chromatographic Retention Behaviors and MS Fragmentation Patterns. Analytical Chemistry, 2020, 92, 21, 14528-14535.

3. Quan-Fei Zhu, Tian-Yi Zhang, Lin-Lin Qin, Xin-Ming Li, Shu-Jian Zheng, and Yu-Qi Feng*, Method to Calculate the Retention Index in Hydrophilic Interaction Liquid Chromatography Using Normal Fatty Acid Derivatives as Calibrants, Analytical Chemistry, 2019, 91: 6057-6063. 

4. Quan-Fei Zhu, Jing-Wen Yan, Tian-Yi Zhang, Hua-Ming Xiao, and Yu-Qi Feng*, Comprehensive screening and identification of fatty acid esters of hydroxy fatty acids in plant tissues by chemical isotope labeling-assisted liquid chromatography-mass spectrometry, Analytical Chemistry, 2018, 90: 10056-10063.

5. Quan-Fei Zhu, Ya-Hui Ge, Na An, Na Li, Ying Xiao, Guo-Xin Huang, Li-Li Zhang, Yu-Qi Feng,* Jian-Lin Wu*, Profiling of Branched Fatty Acid Esters of Hydroxy Fatty Acids in Teas and Their Potential Sources in Fermented Tea. Journal of Agricultural and Food Chemistry, 2022, 70, 5369-5376.

6. Quan-Fei Zhu, Jing-Wen Yan, Jian Ni, Yu-Qi Feng*, FAHFA footprint in the visceral fat of mice across their lifespan. BBA - Molecular and Cell Biology of Lipids, 2020, 1865:158639.

7. Na An †, Quan-Fei Zhu †, Lei Yu, Yong-Ting Chen, Sheng-Li Chen, Yu-Qi Feng*, Derivatization assisted LC-p-MRM-MS with high CID voltage for rapid analysis of brassinosteroids. Talanta 2020, 217: 121058

8. Quan-Fei Zhu, Jing-Wen Yan, Yang Gao, Jing Wei-Zhang, Bi-Feng-Yuan, Yu-Qi Feng*: Highly sensitive detemination of fatty acid esters of hydroxyl fatty acids by liquid chromatography-mass spectrometry. Journal of Chromatography B, 2017, 1061-1062: 34-40.

9. Ming-Zhou Liu†, Quan-Fei Zhu†, Yu-Qi Feng, Jiang Yue*: Glutamate affects the production of epoxyeicosanoids within the brain: The up-regulation of brain CYP2J through the MARK-CREB signaling pathway. Toxicology, 2017. 318: 31-38.

10. Quan-Fei Zhu, Zheng Zhang, Ping Liu, Shu-Jian Zheng, Ke Peng, Qian-Yun Deng, Fang Zheng, Bi-Feng Yuan, Yu-Qi Feng*: Analysis of liposoluble carboxylic acids metabolome in human serum by stable isotope labeling coupled with liquid chromatography-mass spectrometry. Journal of Chromatography A, 2016, 1460: 100-109.

11. Quan-Fei Zhu, Yan-Hong Hao, Ming-Zhou Liu, Jiang Yue, Jian Ni, Bi-Feng Yuan, Yu-Qi Feng*: Analysis of cytochrome P450 metabolites of arachidonic acid by stable isotope probe labeling coupled with ultra high-performance liquid chromatography/mass spectrometry. Journal of Chromatography A, 2015, 1410: 154-163. 

12. Quan-Fei Zhu, Chao Ma, Huai-Xia Chen*: A molecular imprint-coared stirrer bar for selective extraction of caffeine, theobromine and theophylline. Microchim Acta, 2014, 181(3): 303-311. 

13.朱泉霏, 郝俊迪, 严靖雯, 王雨, 冯钰锜*：FAHFAs研究进展：生物功能、分析及合成。Progress in Chemistry, 2021, 33(7): 1115- 1125. 

14. Na An, Quan-Fei Zhu*, Yan-Zhen Wang, Cai- Feng Xiong, Yu-Ning Hu, Yu-Qi Feng*, Integration of chemical derivatization and in-source fragmentation mass spectrometry for high-coverage profiling of submetabolomes. Analytical Chemistry, 2021, 93, 32, 11321-11328.

15. Tian-Yi Zhang, Sha Li, Quan-Fei Zhu*, Qing Wang, Dilshad Hussain ,Yu-Qi Feng*, Derivatization for liquid chromatography-electrospray ionization-mass spectrometry analysis of small-molecular weight compounds, TrAC-Trends in Analytical Chemistry, 119 (2019) 115608.

16. Yu-Ning Hu, Jin-Tao Zhan, Quan-Fei Zhu*, Ting Hu, Na An, Zhen Zhou, Yong Liang, Wei Wang, Zhi Han, Jie Wang, Fu-Qiang Xu, Yu-Qi Feng*, A Mathematical Method for Calibrating the Signal Drift in Liquid Chromatography - Mass Spectrometry Analysis. Talanta, 2021, 233, 122511. 

17. Na An, Wen-Jing Cai, Quan-Fei Zhu*, Wei Wang, Dilshad Hussain, Yu-Qi Feng*, Metabolic profiling of organic acids in honey by stable isotope labeling assisted liquid chromatography-mass spectrometry. Journal of Food Composition and Analysis, 2020, 87: 103423. 

18. Yan-Zhen Wang, Peng-Cheng Mei, Pei-Rong Bai, Na An, Jin-Gang He, Jie Wang, Quan-Fei Zhu*, Yu-Qi Feng*, A strategy for screening and identification of new amino acid-conjugated bile acids with high coverage by liquid chromatography-mass spectrometry.  Analytica Chimica Acta, 1239 (2023) 340691.

19. Yu-Ning Hu, Jin-Tao Zhan, Pei-Rong Bai, Na An, Jun-Jie Tan, Yan-Zhen Wang, Quan-Fei Zhu*, Yu-Qi Feng*, In-depth profiling of di(2-ethylhexyl) phthalate metabolic footprints in rats using click chemistry-mass spectrometry probes. Journal of Hazardous Materials, (2023) doi:https://doi.org/10.1016/j.jhazmat.2023.131190.

20.  Yan-Zhen Wang, Yao-Yu Chen, Xin-Ze Wu, Pei-Rong Bai, Na An, Xia-Lei Liu, Quan-Fei Zhu*, Yu-Qi Feng*, Uncovering the Carboxylated Metabolome in Gut Microbiota-Host Co-metabolism: A Chemical Derivatization-Molecular Networking Approach. Analytical Chemistry, 2023, DOI: 10.1021/acs.analchem.3c02353.

 获奖情况

2015：2015国际HPLC及相关技术学术会议最佳墙报奖；

2018：第十二届全国生物医药色谱会，青年论坛优秀奖；

2019：第22届全国色谱学术报告会及仪器展览会，青年论坛优秀奖；

2021：第23届全国色谱学术报告会及仪器展览会 青年论坛优秀奖；

2023：第十二届全国生物医药色谱会，“分离科学青年创新奖”提名奖；

2023：第八届中国中西部地区色谱学术交流会，青年论坛优秀奖；

Educational Experience

• [1]2007.9-2011.6

  湖北大学化学化工学院  | 应用化学  | Bachelor's degree | University graduated

• [2]2011.9-2014.6

  湖北大学化学化工学院  | 分析化学  | Master's degree | With Certificate of Graduation for Study as Master's Candidates

• [3]2014.9-2017.6

  武汉大学化学与分子科学学院  | 分析化学  | Doctoral degree | With Certificate of Graduation for Doctorate Study

Work Experience

• [1] 2020.2-2022.1
  

  澳门科技大学  | 中药质量研究国家重点实验室  | 博士后研究 澳门青年学者计划 
  

• [2] 2018.3-2022.3
  

  武汉大学  | 化学与分子科学学院  | 博士后研究
  

• [3] 2022.4-Now
  

  武汉大学  | 公共卫生学院  | 特聘副研究员