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黄世文

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个人简介

教育与研究经历   1989年毕业于南京大学化学系,获学士学位;1992年于武汉大学化学系获硕士学位,留校从事教学科研工作。2002年于武汉大学化学与分子科学学院获理学博士学位。2000年8月-2002年2月公派赴新加坡Johns Hopkins Singapor...

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个人简介

教育与研究经历

 

1989年毕业于南京大学化学系,获学士学位;1992年于武汉大学化学系获硕士学位,留校从事教学科研工作。2002年于武汉大学化学与分子科学学院获理学博士学位。2000年8月-2002年2月公派赴新加坡Johns Hopkins Singapore Biomedical Center进行合作研究。2000年6月晋升为副教授,2005年6月被聘为博士生导师,2005年11月晋升为教授。

 

研究领域与兴趣

 

生物医用高分子材料

 

教学

主讲武汉大学通识教育课程“材料科学”和高分子化学”

 

承担项目与课题

 

主持并完成国家自然科学基金、湖北省自然科学基金和武汉市青年科技晨光计划项目各1项;作为主要参加者完成国家重点基础研究规划项目(973)、国家自然科学基金重点项目、面上项目、教育部重点科技项目及高等学校博士点专项基金等项目。目前主持国家自然科学基金2项、教育部留学回国人员启动基金1项,作为研究骨干参加国家重点基础研究规划(973)项目、国家自然科学基金重点项目、高等学校科技创新工程重大项目培育资金各1项。

 

发表论文

  1. Peng Na*, Yu Hui, Wang Ziyu, Zhang Yang, Deng Kai, Li Jiami, Lu Linlin, Zou Tao, Liu Yi, Huang Shiwen*. Dendrimer-grafted bioreducible polycation/DNA multilayered films with low cytotoxicity and high transfection ability. Materials Science & Engineering C-Materials for Biological Applications, 2019, 98, 737-745.

  2. Peng Na*, Ding Xiao, Wang Ziyu, Cheng Yang, Gong Zhiwei, Xu Xiangjiao, Gao Xiaofang, Cai Qun, Huang Shiwen, Liu Yi*. Novel dual responsive alginate-based magnetic nanogels for onco-theranostics. Carbohydrate Polymers, 2019, 204, 32-41.

  3. Wang Qian, Li Jia-Mi, Yu Hui, Deng Kai, Zhou Wei, Wang Cai-Xia, Zhang Yang, Li Kun-Heng, Zhuo Ren-Xi, Huang Shi-Wen*. Fluorinated polymeric micelles to overcome hypoxia and enhance photodynamic cancer therapy. Biomaterials Science, 2018, 6, 3096-3107.

  4. Wu Bo, Lu Shu-Ting., Yu Hui, Liao Ru-Fang, Li Huan., Zafitatsimo, B.V.L., Li Yu-Shuang., Zhang Ying, Zhu Xiao-Lei, Liu Hong-Guang, Xu Hai-Bo.*, Huang Shi-Wen*, Cheng Zhen*. Gadolinium-chelate functionalized bismuth nanotheranostic agent for in vivo MRI/CT/PAI imaging-guided photothermal cancer therapy, Biomaterials, 2018, 159, 37-47.

  5. Zhang Yang, Wang Cai-Xia, Huang Shi-Wen*. Aggregation-Induced Emission (AIE) Polymeric Micelles for Imaging-Guided Photodynamic Cancer Therapy. Nanomaterials, 2018, 921.

  6. Wang Cai-Xia, Wu Bo, Zhou Wei, Wang Qian, Yu Hui, Deng Kai, Li Jia-Mi, Zhuo Ren-Xi, Huang Shi-Wen*.Turn-on fluorescent probe-encapsulated micelle as colloidally stable nano-chemosensor for highly selective detection of Al3+ in aqueous solution and living cell imaging. Sensors and Actuators B-Chemical, 2018, 271 225-238.

  7. Xue Yanan, Tao Lijun, Zhou Yang, Liu Jie, Yu Bo, Long Sihui, Huang Shiwen, Yu Faquan*. Enhanced targeted delivery of doxorubicin based on acid induced charge reversal and combinational stimuli-responsive nanocarrier. Advanced Engineering Materials, 2018, 7, 1701151.

  8. Zhou Wei, Yu Hui, Zhang Liu-Jie, Wu Bo, Wang Cai-Xia, Wang Qian, Deng Kai, Zhuo Ren-Xi, Huang Shi-Wen*. Redox-triggered activation of nanocarriers for mitochondria-targeting cancer chemotherapy, Nanoscale, 2017, 43, 17044-17053.

  9. Xue Yanan, Xia Xiaoyang, Yu Bo, Tao Lijun, Wang Qian, Huang Shi-Wen, Yu Faquan*. Selenylsulfide bond-launched reduction-responsive superparamagnetic nanogel combined of acid-responsiveness for achievement of efficient therapy with low side effect. ACS Applied Materials & Interfaces, 2017, 9, 30253-30257.

  10. Wu Bo, Lu Shu-Ting, Deng Kai, Yu Hui, Cui Can, Zhang Yang, Wu Ming, Zhuo Ren-Xi, Xu Hai-Bo, Huang Shi-Wen*. MRI-guided targeting delivery of doxorubicin with reduction-responsive lipid-polymer hybrid nanoparticles. International Journal of Nanomedicine, 2017, 12, 6871-6882.

  11. Wang Cai-Xia, Liu Lei, Wu Bo, Zhang Liu-Jie, Li Shi-Xi, Zhou Wei, Wang Qian, Zhuo Ren-Xi, Huang Shi-Wen*. Lipid-polymer hybrid nanoparticles with aggregation-induced emission (AIE) characteristic for imaging-guided drug delivery. Journal of Controlled Release, 2017, 259, E15-E15.

  12. Wu Bo, Liao Ru-Fang, Liu Lei, Zhang Liu-Jie, Zhuo Ren-Xi, Xu Hai-Bo, Huang Shi-Wen*. Co-delivery of doxorubicin and triptolide with reduction-sensitive lipid-polymer hybrid nanoparticles for synergistic cancer treatment. Journal of Controlled Release, 2017, 259, E13-E13.

  13. Wu Bo, Wan Bing, Lu Shu-Ting, Deng Kai, Li Xiao-Qi, Wu Bao-Lin, Li Yu-Shuang, Liao Ru-Fang, Huang Shi-Wen*, Xu Hai-Bo*. Near-infrared light-triggered theranostics for tumor-specific enhanced multimodal imaging and photothermal therapy. International Journal of Nanomedicine, 2017, 12, 4467-4478.

  14. Wu Bo, Lu Shu-Ting, Zhang Liu-Jie, Zhuo Ren-Xi, Huang Shi-Wen*. Codelivery of doxorubicin and triptolide with reduction-sensitive lipid-polymer hybrid nanoparticles for in vitro and in vivo synergistic cancer treatment. International Journal of Nanomedicine, 2017, 12, 1853-1862.

  15. Zhang Liu-Jie, Wu Bo, Zhou Wei, Wang Cai-Xia, Wang Qian, Yu Hui, Zhuo Ren-Xi, Liu Zhi-Lan*, Huang Shi-Wen*. Two-component reduction-sensitive lipid-polymer hybrid nanoparticles for triggered drug release and enhanced in vitro and in vivo anti-tumor efficacy. Biomaterials Science, 2017, 5, 98-110.

  16. Song Meifang, Xue Yanan, Lin Xiao, Xia Xiaoyang, Chen Lidi, Zhang Liujie, Yu Bo, Long Sihui, Huang Shiwen, Yu Faquan*. Achievement of release mode under combinational stimuli by acid and reduction for reduced adverse effect in antitumor efficacy. Macromolecular Materials and Engineering, 2016, 301, 1255-1266.

  17. Song Meifang, Xue Yanan, Chen Lidi, Xia Xiaoyang, Zhou Yang, Liu Lei, Yu Bo, Long Sihui, Huang Shiwen, Yu Faquan*. Acid and reduction stimulated logic "and"-type combinational release mode achieved in DOX-loaded superparamagnetic nanogel. Materials Science & Engineering C-Materials for Biological Applications, 2016, 65, 354-363.

  18. Zhang Liujie, Kuang Ying, Liu Jia, Liu Zhilan*, Huang Shiwen*, Zhuo Renxi. Long circulating anionic liposomes for hepatic targeted delivery of cisplatin. RSC Advance, 2016, 6, 76905-76914.

  19. Li Shi-Xi, Liu Lei, Zhang Liu-Jie, Wu Bo, Wang Cai-Xia, Zhou Wei, Zhuo Ren-Xi, Huang Shi-Wen*. Synergetic enhancement of antitumor efficacy with charge-reversal and reduction-sensitive polymer micelles. Polymer Chemistry, 2016, 7, 5113-5122.

  20. Liu Lei, Yu Ping, Zhang Yang, Wu Bo, Cui Can, Wu Ming, Wang Cai-Xia, Zhuo Ren-Xi, Huang Shi-Wen*. Doxorubicin-conjugated magnetic iron oxide nanoparticles for pH-sensitive and magnetic responsive drug delivery. Journal of Controlled Release, 2015, 213, E67-E67.

  21. Wu Bo, Cui Can, Liu Lei, Yu Ping, Zhang Yang, Wu Ming, Zhang Liu-Jie, Zhuo Ren-Xi, Huang Shi-Wen*. Co-delivery of doxorubicin and amphiphilic derivative of Gd-DTPA with lipid-polymer hybrid nanoparticles for simultaneous imaging and targeted therapy of cancer. Journal of Controlled Release, 2015, 213, E13-E14.

  22. Zhang Liu-Jie, Kuang Ying, Zhuo Ren-Xi, Liu Zhi-Lan, Huang Shi-Wen*. Anionic long circulating liposomes for hepatic targeted delivery of cisplatin. Journal of Controlled Release, 2015, 213, E72-E72.

  23. Zhang Yang, Yu Ping, Liu Lei, Wu Bo, Cui Can, Wu Ming, Zhang Liu-Jie, Zhuo Ren-Xi, Huang Shi-Wen*. Lipid-polymer hybrid nanoparticles for the delivery of gemcitabine. Journal of Controlled Release, 2015, 213, E128-E129.

  24. Cui Can, Yu Ping, Wu Ming, Zhang Yang, Liu Lei, Wu Bo, Wang Cai-Xia, Zhuo Ren-Xi, Huang Shi-Wen*. Reduction-sensitive micelles with sheddable PEG shells self-assembled from a Y-shaped amphiphilic polymer for intracellular doxorubicine release. Colloids and Surfaces B-Biointerfaces, 2015, 129, 137-145.

  25. Chen Lidi, Xue Yanan, Xia Xiaoyang, Song Meifang, Huang Juan, Zhang Han, Yu Bo, Long Sihui, Liu Yanping, Liu Lei, Huang Shiwen, Yu faquan*. A redox stimuli-responsive superparamagnetic nanogel with chemically anchored DOX for enhanced anticancer efficacy and low systemic adverse effects. Journal of Materials Chemistry B, 2015, 3, 8949-8962.

  26. Liu Lei, Wu Bo, Yu Ping, Zhuo Ren-Xi, Huang Shi-Wen*. Sub-20 nm nontoxic aggregation-induced emission micellar fluorescent light-up probe for highly specific and sensitive mitochondrial imaging of hydrogen sulfide, Polymer Chemistry, 2015, 6, 5185-5189.

  27. Wu Bo, Yu Ping, Cui Can, Wu Ming, Zhang Yang, Liu Lei, Wang Cai-Xia, Zhuo Ren-Xi, Huang Shi-Wen*. Folate-containing reduction-sensitive lipid-polymer hybrid nanoparticles for targeted delivery of doxorubicin. Biomaterials Science, 2015, 3, 655-664.

  28. Yu Ping, Xia Xi-Ming, Wu Ming, Cui Can, Zhang Yang, Liu Lei, Wu Bo, Wang Cai-Xia, Zhang Liu-Jie, Zhou Xiang, Zhuo Ren-Xi, Huang Shi-Wen*. Folic acid-conjugated iron oxide porous nanorods loaded with doxorubicin for targeted drug delivery. Colloids and Surfaces B-Biointerfaces, 2014, 120, 142-151.

  29. Cui Can, Xue Ya-Nan, Wu Ming, Zhang Yang, Yu Ping, Zhuo Ren-Xi, Huang Shi-Wen*. Polymer-lipid hybrid nanoparticles with reduction-triggered release for improved antitumor efficiency. Journal of Controlled Release, 2013, 172, E17-E17.

  30. Wu Ming, Xia Xi-Ming, Cui Can, Yu Ping, Zhang Yang, Liu Lei, Zhuo Ren-Xi, Huang Shi-Wen*. Highly efficient loading of amorphous paclitaxel in mesoporous hematite nanorods and their in vitro antitumor activity. Journal of Controlled Release, 2013, 172, E56-E57.

  31. Cui Can, Xue Ya-Nan, Wu Ming, Zhang Yang, Yu Ping, Liu Lei, Zhuo Ren-Xi, Huang Shi-Wen*. Poly(L-aspartamide)-based reduction-sensitive micelles as nanocarriers to improve doxorubicin content in cell nuclei and to enhance antitumor activity. Macromolecular Bioscience, 2013, 13, 1036-1047.

  32. Peng Lin, Gao Yuan, Xue Ya-Nan, Huang Shi-Wen*, Zhuo Ren-Xi*. The effectiveness, cytotoxicity, and intracellular trafficking of nonviral vectors for gene delivery to bone mesenchymal stem cells. Journal of Bioactive and Compatible Polymers, 2013, 28, 204-217.

  33. Cui Can, Xue Ya-Nan, Wu Ming, Zhang Yang, Yu Ping, Liu Lei, Zhuo Ren-Xi, Huang Shi-Wen*. Cellular uptake, intracellular trafficking, and antitumor efficacy of doxorubicin-loaded reduction-sensitive micelles, Biomaterials, 2013, 34, 3858-3869.

  34. Wu Ming, Xia Xi-Ming, Cui Can, Yu Ping, Zhang Yang, Liu Lei, Zhuo Ren-Xi, Huang Shi-Wen*. Highly efficient loading of amorphous paclitaxel in mesoporous hematite nanorods and their in vitro antitumor activity. Journal of Materials Chemistry B, 2013, 1, 1687-1695.

  35. Wang Changcheng, Zheng Xiaolong, Huang Rong, Yan Shengyong, Xie Xia, Tian Tian, Huang Shiwen, Weng Xiaocheng, Zhou Xiang*. A 4-Amino-1,8-Naphthalimide Derivative for Selective Fluorescent Detection of Palladium(II) Ions. Asian Journal of Organic Chemistry, 2012, 1, 259-263.

  36. Liu Wen-Ming, Liu Min, Xue Ya-Nan, Peng Na, Xia Xi-Ming, Zhuo Ren-Xi, Huang Shi-Wen. Poly(amidoamine)s with pendant primary amines and flexible backbone for enhanced nonviral gene delivery: Transfection and intracellular trafficking. Journal of Biomedical Materials Research Part A, 2012, 100A, 872-881.

  37. He Wen-Tao, Xue Ya-Nan, Liu Wen-Ming, Huang Shi-Wen*, Zhuo Ren-Xi. One-pot preparation of polyethlyenimine/silica hybride nanoparticles as serum-resistant gene delivery vectors: Transfection and intracellular trafficking. Journal of Controlled Release, 2011, 152, E145-E146.

  38. Liu Wen-Ming, Xue Ya-Nan, He Wen-Tao, Zhuo Ren-Xi, Huang Shi-Wen*. Dendrimer modified magnetic iron oxide nanoparticle/DNA/PEI ternary complexes: A novel strategy for magnetofection. Journal of Controlled Release, 2011, 152, E159-E160.

  39. Peng Na, Xue Ya-Nan, Xia Xi-Ming, Huang Shi-Wen*, Zhuo Ren-Xi. Bioreducible cationic micelle/DNA multilayered films for localized gene delivery. Journal of Controlled Release, 2011, 152, E166-E167.

  40. Xia Xi-Ming, Yu Ping, Peng Na, Zhang Yang, Xue Ya-Nan, Zhuo Ren-Xi, Huang Shi-Wen*. Tunable release of biomacromolecules from reductive-responsive multilayered hollow microcapsules. Journal of Controlled Release, 2011, 152, E101-E103.

  41. Xu Ya-Nan, Liu Lei, Ji Xiao, Huang Shi-Wen*, Zhuo Ren-Xi. Bioreducible polycationic micelles for in vitro gene delivery. Journal of Controlled Release, 2011, 152, E177-E179.

  42. Liu Min, Chen Biao, Xue Yanan, Huang Jie, Zhang Liming, Huang Shiwen, Li Qingwen, Zhang Zhijun*. Polyamidoamine-grafted multiwalled carbon nanotubes for gene delivery: synthesis, transfection and intracellular trafficking. Bioconjugate Chemistry, 2011, 22, 2237-2243.

  43. Xue Yanan, Zhang Min, Liu Lei, Li Wenxi, Huang Shiwen*. Polyaspartamides grafted with 1-(3-aminopropyl)imidazole as less toxic and highly efficient gene carriers. Acta Polymerica Sinica, 2011, (8), 874-882.

  44. Peng Na, Xia Xi-Ming, He Wen-Tao, Liu Wen-Ming, Huang Shi-Wen*, Zhuo Ren-Xi*. Fabrication and stability of porous poly(allylamine) hydrochloride (PAH)/poly(acrylic acid) (PAA) multilayered films via a cleavable-polycation template. Polymer, 2011, 52, 1256-1262.

  45. Liu Wen-Ming, Xue Ya-Nan, Peng Na, He Wen-Tao, Zhuo Ren-Xi, Huang Shi-Wen*. Dendrimer modified magnetic iron oxide nanoparticle/DNA/PEI ternary magnetoplexes: a novel strategy for magnetofection. Journal of Materials Chemistry, 2011, 21, 13306-13315.

  46. He Wen-Tao, Xue Ya-Nan, Peng Na, Liu Wen-Ming, Zhuo Ren-Xi*, Huang Shi-Wen*. One-pot preparation of polyethylenimine-silica nanoparticles as serum-resistant gene delivery vectors: Intracellular trafficking and transfection. Journal of Materials Chemistry, 2011, 21, 10496-10503.

  47. Zhang Min, Xue Ya-Nan, Liu Min, Zhuo Ren-Xi, Huang Shi-Wen*. Biocleavable Polycationic Micelles as Highly Efficient Gene Delivery Vectors. Nanoscale Research Letter, 2010, 5, 1804-1811.

  48. Peng Lin, Gao Yuan, XueYa-Nan, Huang Shi-Wen*, Zhuo Ren-Xi*. Cytotoxicity and in vivo tissue compatibility of poly(amidoamine) with pendant aminobutyl group as a gene delivery vector. Biomaterials, 2010, 31, 4467-4476.

  49. Liu Min, Chen Jun, Cheng Yan-Ping, Xue Ya-Nan, Zhuo Ren-Xi, Huang Shi-Wen*.Novel Poly(amidoamine)s with Pendant Primary Amines as Highly Efficient Gene Delivery Vectors. Macromolecular Bioscience, 2010, 10, 384-392.

  50. Xue Ya-Nan, Liu Min, Peng Lin, Huang Shi-Wen*, Zhuo Ren-Xi. Improving Gene Delivery Efficiency of Bioreducible Poly(amidoamine)s via Grafting with Dendritic Poly(amidoamine)s. Macromolecular Bioscience, 2010, 10, 404-414.

  51. Liu Min, Chen Jun, Xue Ya-Nan, Liu Wen-Ming, Zhuo Ren-Xi, Huang Shi-Wen*. Poly(beta-aminoester)s with Pendant Primary Amines for Efficient Gene Delivery. Bioconjugate Chemistry, 2009, 20, 2317-2323.

  52. Peng Lin, Liu Min, Xue Ya-Nan, Huang Shi-Wen*, Zhuo Ren-Xi*. Transfection and intracellular trafficking characteristics for poly(amidoamine)s with pendant primary amine in the delivery of plasmid DNA to bone marrow stromal cells. Biomaterials, 2009, 30, 5825-5833.

  53. Xue Ya-Nan, Huang Zhen-Zhen, Zhang Jian-Tao, Liu Min, Zhang Min, Huang Shi-Wen*, Zhuo Ren-Xi*.Synthesis and self-assembly of amphiphilic poly(acrylic acid-b-DL-lactide) to form micelles for pH-responsive drug delivery. Polymer, 2009, 50, 3706-3713.

  54. Zhang Min, Liu Min, Xue Ya-Nan, Huang Shi-Wen*, Zhuo Ren-Xi*. Polyaspartamide-Based Oligo-ethylenimine Brushes with High Buffer Capacity and Low Cytotoxicity for Highly Efficient Gene Delivery. Bioconjugate Chemistry, 2009, 20 440-446.

  55. Zhang Jian-Tao*, Xue Ya-Nan, Gao Fa-Zhi, Huang Shi-Wen*, Zhuo Ren-Xi. Preparation of temperature-sensitive poly(N-isopropylacrylamide)/beta- cyclodextrin-grafted polyethylenimine hydrogels for drug delivery. Journal of Applied Polymer Science, 2008, 108, 3031-3037.

  56. Huang Shi-Wen, Zhuo Ren-Xi*. Recent advances in polyphosphoester and polyphosphoramidate-based biomaterials. Phosphorus Sulfur and Silicon and the Related elements, 2008, 193, 340-348.

  57. Yan Guo-Ping*, Wang Xiao-Yan, Wang Xu-Li, Huang Shi-Wen, Zhuo Ren-Xi. Synthesis and in vitro property study of polyaspartamides. Chinese Journal of Chemistry, 2007, 2, 1748-1753.

  58. Sun Yi-Xin, Zhang Jian-Tao, Huang Shi-Wen, Wang Sheng-Fu. Hydrogen peroxide biosensor based on the bioelectrocatalysis of horseradish peroxidase incorporated in a new hydrogel film. Sensors and Actuators B-Chemical, 2007, 124, 494-500.

  59. Chen Jun, Xia Xi-Ming, Huang Shi-Wen*, Zhuo Ren-Xi*. A cleavable-polycation template method for the fabrication of noncrosslinked, porous polyelectrolyte multilayered films. Advanced Materials, 2007, 19, 979.

  60. Chen Jun, Huang Shi-Wen*, Lin Wen-Hai, Zhuo Ren-Xi*. Tunable film degradation and sustained release of plasmid DNA from cleavable polycation/plasmid DNA multilayers under reductive conditions. Small, 2007, 3, 6-643.

  61. Chen Jun, Huang Shi-Wen*, Liu Min, Zhuo Ren-Xi*. Synthesis and degradation of poly(beta-aminoester) with pendant primary amine. Polymer, 2007, 48, 675-681.

  62. Zhang Jian-Tao, Huang Shi-Wen, Xue Ya-Nan, Zhuo Ren-Xi*. Effect of peg as pore-forming agents on the properties of porous poly(N-isopropylacylamide-co-acrylic acid) hydrogels. Acta Polymerica Sinica, 2006, (3), 418-423.

  63. Zhang Jian-Tao, Huang Shi-Wen, Zhuo Ren-Xi*. A novel sol-gel strategy to prepare temperature-sensitive hydrogel for encapsulation of protein. Colloid and Polymer Science, 2005, 284, 209-213.

  64. Zhang Jian-Tao, Huang Shi-Wen, Xue Ya-Nan, Liu Ji, Zhuo Ren-Xi*. Thermal-sensitive beta-cyclodextrin-containing poly(N-isopropylacrylamide) hydrogels crosslinked by Si-O-Si bonds - Synthesis, characterization and prolonging in vitro release of 5-fluorouracil. Chinese Journal of Polymer Science, 2005, 23, 513-519.

  65. Zhang Jian-Tao, Huang Shi-Wen, Xue Ya-Nan, Zhuo Ren-Xi*. Poly(N-isopropylacrylamide) nanoparticle-incorporated PNIPAAm hydrogels with fast shrinking kinetics. Macromolecular Rapid Communications, 2005, 26, 1346-1350.

  66. Zhang Jian-Tao, Huang Shi-Wen, Liu Ji, Zhuo Ren-Xi*. Temperature sensitive poly [N-isopropylacrylamide-co(acryloyl beta-cyclodextrin)] for improved drug release. Macromolecular Bioscience, 2005, 5, 192-196.

  67. Zhang Xue-Qing, Wang Xu-Li, Huang Shi-Wen, Zhuo Ren-Xi, Liu Zhi-Lan. Mao Hai-Quan*, Leong Kam W. In vitro gene delivery using polyamidoamine dendrimers with a trimesyl core. Biomacromolecules, 2005, 6, 341-350.

  68. Zhang Jian-Tao, Huang Shi-Wen, Gao Fa-Zhi, Zhuo Ren-Xi*. Novel temperature-sensitive, beta-cyclodextrin-incorporated poly(N-isopropylacryl- amide) hydrogels for slow release of drug. Colloid and Polymer Science, 2005, 283, 461-464.

  69. Zhang Jian-Tao, Huang Shi-Wen, Wang Lu-Ling, Zhuo Ren-Xi*. Preparation and characterization of fast-responsive porous poly(N-isopropylacrylamide-co-acrylic acid) hydrogels. Chemical journal of Chinese Universities-Chinese, 2004, 25, 2370-2374.

  70. Zhang Jian-Tao, Huang Shi-Wen, Zhuo Ren-Xi*. Temperature-sensitive polyamidoamine dendrimer/poly (N-isopropylacrylamide) hydrogels with improved responsive properties. Macromolecular Bioscience, 2004, 4, 575-578.

  71. Huang Shi-Wen, Wang Jun, Zhang Peng-Chi, Mao Hai-Quan*, Zhuo Ren-Xi, Leong Kam W. Water-soluble and nonionic polyphosphoester: Synthesis, degradation, biocompatibility and enhancement of gene expression in mouse muscle. Biomacromolecules, 2004, 5, 306-311.

  72. Zhang Jian-Tao, Huang Shi-Wen, Cheng Si-Xue, Zhuo Ren-Xi*. Preparation and properties of poly(N-isoproplyacrylamide)/poly(N-isopropylacrylamide) interpenetrating polymer networks for drug delivery. Journal of Polymer Science Part A-Polymer Chemistry, 2004, 42, 1249-1254.

  73. Wu Xu-Ye, Huang Shi-Wen, Zhang Jian-Tao, Zhuo Ren-Xi*. Preparation and characterization of novel physically cross-linked hydrogels composed of poly(vinyl alcohol) and amine-terminated polyamidoamine dendrimer. Macromolecular Bioscience, 2004, 4, 71-75.

  74. Wu Xu-Ye, Huang Shi-Wen, Zhang Jian-Tao, Zhuo Ren-Xi*. Preparation and properties of physically cross-linked poly(vinyl alcohol)/hydroxy-terminated polyamidoamine dendrimer hydrogels. Chemical journal of Chinese Universities-Chinese, 2004, 25, 382-384.

  75. Zhang Jian-Tao, Huang Shi-Wen, Zhuo Ren-Xi*.Preparation and characterization of novel temperature sensitive poly (N-isopropylacrylamide-co-acryloyl beta-cyclodextrin) hydrogels with fast shrinking kinetics. Macromolecular Chemistry and Physics, 2004, 205, 107-113.

  76. Wang Jun, Huang Shi-Wen, Zhang Peng-Chi Mao Hai-Quan, Leong Kam W. Effect of side-chain structures on gene transfer efficiency of biodegradable cationic polyphosphoesters. International Journal of Pharmaceutics, 003, 265, 75-84.

  77. Huang Shi-Wen, Zhuo Ren-Xi*. Recent progress in polymer-based gene delivery vectors. Chinese Science Bulletin, 2003, 48, 1304-1309.

  78. Huang Shi-Wen, Fu Lie-Zhen, Zhang Xue-Qing, Liu Hui, Li Wen-Xi, Zhuo Ren-Xi*. Syntheses of polyamidoamine dendrimers starting from a hexadimensional core and application in gene transfer. Science in China Series B-Chemistry, 2003, 46, 271-279.

  79. Zhang Jian-Tao, Cheng Si-Xue, Huang Shi-Wen, Zhuo Ren-Xi*.Temperature-sensitive poly (N-isopropylacrylamide) hydrogels with macroporous structure and fast response rate. Macromolecular Rapid Communications, 2003, 24, 447-451.

  80. Wang Xu-Li, Zhuo Ren-Xi*, Huang Shi-Wen, Liu Li-Jian. Synthesis, characterization and in vitro cytotoxicity of poly [(5-benzyloxy-trimethylene carbonate)-co-(trimethylene carbonate)]. Macromolecular Chemistry and Physics, 2002, 203, 985-990.

  81. Huang Shi-Wen, Guo Feng, Shan Zi-Xing, Zhao De-Jie*. Insertion of dichlorocarbene into C-B bond of borinates under liquid-liquid phase transfer catalysis conditions: A convenient preparation of unsymmetrical ketones. Chinese Journal of Chemistry, 2001, 19, 202-204.

  82. Huang Shi-Wen, Peng Wei-Li, Shan Zi-Xing, Zhao De-Jie. A new facile approach to highly selective hydroboration of alkenes with sodium malonyloxyborohydride. New Journal of Chemistry, 2001, 25, 869-871.

  83. Guo Feng, Huang Shi-Wen, Shan Zi-Xing, Zhao De-Jie*. A convenient preparation of unsymmetrical ketones from borinates using phase transfer catalysis. Journal of Chemical Research-S, 2000, 6, 280-281.

  84. Huang Shi-Wen, Wang Bo, Shan Zi-Xing, Zhao De-Jie*. Asymmetric reduction of acetophenone with borane catalyzed by chiral oxazaborolidinones derived from L-alpha-amino acids. Synthetic Communications, 2000, 30, 2423-2429.

  85. Peng Wei-Li, Huang Shi-Wen, Shan Zi-Xing, Zhao De-Jie*. Selective hydroboration of alkene with sodium malonyloxyborohydride. Chinese Journal of Organic Chemistry, 1999, 19, 72-76.

  86. Shan Zi-Xing, Cheng Fu-Yong, Huang Shi-Wen, Zhao De-Jie*. An improved approach to (R)-(+)-1,1'-bi-2-naphthol of 100% enantiomeric excess via a cyclic borate ester. Tetrahedron Asymmetry, 1997, 8, 1175-1177.

 

获奖与荣誉

 

获2000年湖北省自然科学二等奖和2006年湖北省自然科学一等奖各一项。

 


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