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3.中药质量评价新方法及中药功效的科学表征

3.1中药质量评价新方法

[1]Comparative metabolic profiling of wild Cordyceps species and their substituents by liquid chromatography-tandem mass spectrometry,Frontiers in Pharmacology,2022,13:1036589(各品类冬虫夏草代谢物特征标志物筛选及代谢物全成分解析)

[2]Lipidomic profiling of wild cordyceps and its substituents by liquid chromatography-electrospray ionization-tandem mass spectrometry,LWT - Food Science and Technology, 2022, 163: 113497(各品类冬虫夏草脂质特征标志物筛选及全脂质成分解析)

[3]Fast quantification of free amino acids in food by microfluidic voltage-assisted liquid desorption electrospray ionization-tandem mass spectrometry,Analytical and bioanalytical chemistry,2020,412(8):1947-1954(食品及冬虫夏草中游离氨基酸快速定量检测新方法—微流体电压辅助液体解吸电喷雾电离串联质谱法)

[4]Quantification of Aromatic Amino Acids in Cordyceps fungi by Micellar Electrokinetic Capillary Chromatography,Wuhan University Journal of Natural Sciences,2019,24(3):245-250(冬虫夏草中芳香族氨基酸检测新方法)

[5]Profiling metals in Cordyceps sinensis by using inductively coupled plasma mass spectrometry,Analytical methods : advancing methods and applications,2017,9(4):724-72(各品类冬虫夏草中重金属研究)

[6]Identification of chemical markers in Cordyceps sinensis by HPLC-MS/MS,Analytical and bioanalytical chemistry,2015,407(26):8059-66(各品类冬虫夏草特征标志物组合的筛选)

[7]Simultaneous quantification of adenosine and deoxyadenosine isomers in foods with high sensitivity,Analytical Methods,2019,11(38):4946-4950(食品及冬虫夏草中特定异构体成分高灵敏检测新方法)

3.2冬虫夏草专利授权 

[1]一种高效液相色谱法测定虫草中虫草素含量的方法.第一发明人.ZL201910699621.6

3.3中药功效的科学表征研究(质谱—多维组学)

[1]Multi-omics analysis reveals the healthy functions of Oviductus Ranae,Pharmacological Research - Modern Chinese Medicine, 2024, 10: 100369  (多组学分析揭示哈蟆油<雪蛤>的保健功效)

[2]基于宏基因组技术研究哈蟆油对大鼠肠道菌群的影响[J].药物流行病学杂志,2023,32(09):1008-1016.DOI:10.19960/j.issn.1005-0698.202309007

[3]基于宏基因组学技术研究生态繁育冬虫夏草对大鼠肠道菌群的影响[J].中国药师,2022,25(12):2137-2143.DOI:10.19962/j.cnki.issn1008-049X.2022.12.013

[4]基于网络药理学和分子对接研究冬虫夏草治疗糖尿病肾病的作用机制[J].中国药师,2021,24(06):1057-1063