研究领域
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1、 肿瘤分子流行病学、前瞻性和专病队列研究建设；
2、肿瘤遗传调控精细解析（DNA/RNA/Protein/microbes/TME 分子视角）；
3、基于跨维度多组学数据，研发AI算法智能设计和合成功能元件；
4、基因-环境交互作用和环境表观应对机制模式探析；
5、肿瘤早期筛查和疾病风险预测模型构建；
论文成果
- Can Chen#, Yimin Cai#, Wenlong Hu#, Kai Tan#, Zequn Lu#, Xuanyu Zhu#, ......, Jianbo Tian* & Xiaoping Miao*.Single-cell eQTL mapping reveals cell subtype-specific genetic control and mechanism in malignant tr.Cancer Discovery 2025 (IF:30.6, 中科院1区)
- Yimin Cai#, Zequn Lu#, Can Chen#, Ying Zhu#, ...... ，Jianbo Tian* & Xiaoping Miao*..An atlas of genetic effects on cellular composition of the tumor microenvironment.Nat Immunol 2024 (IF:27.7，中科院1区)
- Cai Yimin#, Lu Zequn#, Li Bin# ...... Miao Xiaoping*, Zhang Shaokai*, Wei Yongchang*, Tian Jianbo*.Genome-wide enhancer RNA profiling adds molecular links between genetic variation and human cancers.Mil Med Res 2024.11(1):36 (IF:16.7, 中科院1区)
- Tian Jianbo*，Zhang Ming#, Zhang Fuwei#, Gao Kai# ...... Jin Mingjuan*, Miao Xiaoping*, Chen Kun*..Developing an optimal stratification model for colorectal cancer screening and reducing racial dispa.Genome Medicine 2024,16(1):81（IF:10.4, 中科院1区）
- Ying Pingting#, Chen Can#, Lu Zequn #, ...... ,Tian Jianbo*, Miao Xiaoping*..Genome-wide enhancer-gene regulatory maps link causal variants to target genes underlying human canc.Nature communications 2023,14(1):5958（IF:16.6, 中科院1区）
专利
科研项目
科研团队
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