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杨志刚
-
硕士生导师
- 性别：男
- 学历：研究生毕业
- 在职信息：在职
- 所在单位：药学院
- 学科：
药物化学
- 办公地点：一号楼五楼
- 电子邮箱：04e105b080459e7fca5cd2dabaab2f62445479d2735c638a674088cd759f8900e42410663906d37a77b2b01471f5f56e37e83709275d43c48ea705bb9ba936f2b7893a669b3e5fe82c433c3bd741cac73ae756a2a4f63fab415bbd27b4147eb3d5e26bb2194f999f1768e0a5fed52892a65c38727fa969d64736e67f3d39aa98
- 2024年，荣获武汉大学第一届实验室安全技能竞赛二等奖
- 2020年，荣获武汉大学网络实验室安全知识竞赛——实验室安全知识达人
- 2020年，荣获药学院青年教师教学竞赛三等奖
- 2018年，荣获药学院青年教师教学竞赛二等奖
- 2017年，入选武汉大学珞珈青年学者
- 2016年，入选“3551光谷人才计划”创业人才
- 2013年，入选湖北省楚天学者计划——楚天学子
访问量：
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[1].
Qianying Zhou
, Mi Huang
, Yongcun Shen
, Zhenling Chen*
, Liying Xu
和 Zhigang Yang*.
Synthesis of gem-Difluorinated 2,3-Dihydrobenzofurans Using Freon-22 via [4+1] Annulation of Difluorocarbene and Antitumor Activity Evaluation.
Org. Lett. 2024, 26, 1212−1217.
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[2].
Xiangyu Li
, Na Li
, Lan Yang
, Rui Jiang
, Yong He
, Jian Shi
, Zhong-Xing Jiang
和 Zhigang Yang*.
Switchable Nucleophilic Site Enables Expedient Synthesis of CF3‑Containing Thiazoles and Allenes from 1,3-Enynes.
ACS Catal. 2023, 13, 12755−12765.
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[3].
Yuyin Mao
, Na Li
, Jie Liu*
, Zhong-Xing Jiang
和 Zhigang Yang*.
TBAF-Mediated [3+1] Cycloaddition of Difluorocarbene to Access gem-Difluorinated 1,2-Diazetidine Analogues as Potent Anticancer Agents.
Org. Lett. 2023, 25, 7567−7572.
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[4].
Yushan Xiao
, Yimin Jia
, Jinfeng Huang
, Xiangyu Li
, Zhiwen Zhou
, Jing Zhang
, Mou Jiang
, Xin Zhou
, Zhong-Xing Jiang*
和 Zhigang Yang*.
Synthesis of SCF3-Substituted Sulfonium Ylides from Sulfonium Salts or α-Bromoacetic Esters.
Adv. Synth. Catal. 2022, 364, 738−743.
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[5].
Yimin Jia
, Yuan Yuan
, Jinfeng Huang
, Zhong-Xing Jiang*
和 Zhigang Yang*.
Synthesis of Difluorinated Heterocyclics through Metal-Free [8+1] and [4+1] Cycloaddition of Difluoro- carbene.
Org. Lett. 2021, 23, 2670−2675.
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[6].
Jinfeng Huang
, Yimin Jia
, Xiangyu Li
, Jianli Duan
, Zhong-Xing Jiang
和 Zhigang Yang*.
Halotrifluoromethylation of 1,3-Enynes: Access to Tetrasubstituted Allenes.
Org. Lett. 2021, 23, 2314−2319.
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[7].
Na Wang
, Yimin Jia
, Hongmei Qin
, Zhong-Xing Jiang
和 Zhigang Yang*.
Chlorotrifluoromethylthiolation of Sulfur Ylides for the Formation of Tetrasubstituted Trifluoromethylthiolated Alkenes.
Org. Lett. 2020, 22, 7378−7382.
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[8].
Hongmei Qin
, Yimin Jia
, Na Wang
, Zhong-Xing Jiang
和 Zhigang Yang*.
Practical and regioselective halotrifluoromethylthiolation of sulfur ylides.
Chem. Commun. 2020, 56, 8265−8268.
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[9].
Ying Zheng
, Yimin Jia
, Yuan Yuan
, Zhong-Xing Jiang*
和 Zhigang Yang*.
F−-Free Deoxyhydro- trifluoromethylation of α‑Keto Esters with Ph3P+CF2CO2−: Synthesis of α-CF3- Substituted Esters.
J. Org. Chem. 2020, 85, 10913−10923.
-
[10].
Jing Zhang
, Yuan Yuan
, Yu Li
, Hao Yang
, Huaibin Zhang
, Shizhen Chen
, Xin Zhou
, Zhigang Yang*
和 Zhong-Xing Jiang*.
Synthesis of Branched Monodisperse Oligoethylene Glycols and 19F MRI-Traceable Biomaterials through Reductive Dimerization of Azides.
J. Org. Chem. 2020, 85, 6778−6787.
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[11].
Yimin Jia
, Hongmei Qin
, Na Wang
, Zhong-Xing Jiang
和 Zhigang Yang*.
Fe2O3‑Promoted Intermolecular Chlorotrifluoromethylthiolation of Alkenes.
J. Org. Chem. 2018, 83, 2808−2817.
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[12].
Yimin Jia
, Long Chen
, Huaibin Zhang
, Ying Zheng
, Zhong-Xing Jiang
和 Zhigang Yang*.
Electrophilic chloro(ω-alkoxy)lation of alkenes employing 1-chloro-1,2-benziodoxol-3-one: facile synthesis of β-chloroethers.
Org. Biomol. Chem. 2018, 16, 7203−7213.
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[13].
Haotian Xing
, Long Chen
, Yimin Jia
, Zhongxing Jiang*
和 Zhigang Yang*.
Fe2O3-catalyzed Pummerer rearrangement of acyl chlorides and sulfoxides: Facile synthesis of alkylthiomethyl ester.
Tetrahedron Lett. 2017, 58, 2199−2202.
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[14].
Mingyang Fu
, Long Chen
, Yongpeng Jiang
, Zhong-Xing Jiang*
和 Zhigang Yang*.
Copper-Catalyzed Intermolecular Chloro- and Bromotrifluoromethylation of Alkenes.
Org. Lett. 2016, 18, 348−351.
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[15].
Long Chen
, Haotian Xing
, Huaibin Zhang
, Zhong-Xing Jiang*
和 Zhigang Yang*.
Copper-catalyzed intermolecular chloroazidation of α,β-unsaturated amides.
Org. Biomol. Chem. 2016, 14, 7463−7467.
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[16].
Zihong Wan
, Yu Li
, Shaowei Bo
, Ming Gao
, Xuemeng Wang
, Kai Zeng
, Xin Tao
, Xuefei Li
, Zhigang Yang*
和 Zhong-Xing Jiang*.
Amide bond-containing monodisperse polyethylene glycols beyond 10 000 Da.
Org. Biomol. Chem. 2016, 14, 7912−7919.
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[17].
Guiquan Xia
, Yu Li
, Zhigang Yang*
和 Zhong-Xing Jiang*.
Development of a Scalable Process for α-Amino-ω-methoxyldodecaethylene Glycol.
Org. Process Res. Dev. 2015, 19, 1769−1773.
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[18].
Yu Li
, Qi Guo
, Xuefei Li
, Hua Zhang
, Fanghua Yu
, Weijiang Yu
, Guiquan Xia
, Mingyang Fu
, Zhigang Yang*
和 Zhong-Xing Jiang*.
Fluorous synthesis of mono-dispersed poly(ethylene glycols).
Tetrahedron Lett. 2014, 55, 2110−2113.
-
[19].
Zhigang Yang
和 Jianrong (Steve) Zhou*.
Palladium-Catalyzed, Asymmetric Mizoroki−Heck Reaction of Benzylic Electrophiles Using Phosphoramidites as Chiral Ligands.
J. Am. Chem. Soc. 2012, 134, 11833−11835.
