1997. 9 - 2001. 6       Wuhan University   B.S.

2001. 9 - 2006. 6       Wuhan University   Ph.D

2006. 11 - 2007. 6     National University of Singapore      Postdoc

2007. 7 - 2010. 12     University of California, Riverside     Postdoc

2011. 1 -                    Wuhan University                             Professor

Bi-Feng Yuan studied biochemistry and biophysics at Wuhan University in China, where he received his BSc and Ph.D. degrees in 2001 and 2006, respectively. From 2006-2007 and 2007-2010, he worked as a postdoctoral researcher in the Department of Biological Sciences at National University of Singapore and in the Department of Chemistry at University of California Riverside, respectively. He joined Wuhan University in 2011 and is currently a Professor in the School of Public Health.

Research Areas
1. Environmental Pollutants and Their Impact on Health
We develop novel detection technologies with high sensitivity and high coverage for environmental pollutants. Using big data analysis and machine learning, we investigate the effects of environmental pollutants on health. Through association analyses of the exposome and health outcomes, combined with cellular and animal experiments, we identify key environmental factors that substantially affect health and elucidate their toxicological mechanisms.

2. Environmental Epigenetics
Nucleic acid epigenetic modifications play important roles in gene regulation and are critical in the development of various diseases, including cancer. By establishing highly sensitive and specific analytical methods such as mass spectrometry and sequencing, combined with bioinformatics and big data analysis, we conduct in-depth studies on the physiological functions of nucleic acid epigenetic modifications and explore the effects and mechanisms of environmental factors on these modifications.

3. Metabolomics
We develop mass spectrometry-based metabolomics methods. By integrating advanced data analysis and machine learning tools, we identify disease biomarkers, explore the physiological functions of metabolites during disease onset and progression, and investigate the effects and mechanisms of environmental factors on metabolism in living organisms, thereby providing new strategies and insights for the prevention, diagnosis, and treatment of related diseases.