Research

Bi-Feng Yuan studied biochemistry and biophysics at Wuhan University in China,  where he received his BSc and Ph.D. degrees in 2001 and 2006,  respectively. From 2006-2007 and 2007-2010, he worked as a postdoctoral  researcher in the Department of Biological Sciences at National  University of Singapore and in the Department of Chemistry at University  of California Riverside, respectively. He joined Wuhan University in  2011 and is currently a Professor in the School of Public Health.

1. Environmental epigenetics

Epigenetic  modifications of nucleic acids play a crucial role in gene regulation  and are key players in the development of various diseases, including  cancer. Our research is dedicated to investigating the physiological  functions of epigenetic modifications of nucleic acids by establishing  sensitive and specific analytical methods such as mass spectrometry and  sequencing techniques. Additionally, we explore the impact and  mechanisms of environmental factors on epigenetic modifications, aiming  to provide new strategies and insights for the prevention and treatment  of related diseases.

2. Metabolomics

We  are dedicated to developing metabolomics research methods based on mass  spectrometry technology, in conjunction with appropriate biological  approaches, to identify disease biomarkers. Our research aims to  comprehensively explore the vital physiological functions of metabolites  in disease occurrence and progression, while also investigating the  impact and mechanisms of environmental factors on life metabolism. Our  goal is to provide novel strategies and insights for the prevention,  diagnosis, and treatment of related diseases.

3. Investigation of Environmental Pollutants and Their Impact on Health

Develop  new technologies for the detection of environmental pollutants with  high sensitivity and wide coverage, and explore the impact of  environmental pollutants on human health. Through correlation analysis  of environmental pollutants and health outcomes, identify key  environmental factors that significantly affect human health.