标题：
Effect of ambient fine particulates (PM2.5) on hospital admissions for respiratory and cardiovascular diseases in Wuhan, China
点击次数：
影响因子：
5.8
DOI码：
10.1186/s12931-021-01731-x
教研室：
Wuhan University School of Health Sciences
发表刊物：
Respiratory research
刊物所在地：
England
关键字：
Air pollution; Particulate matter; Spatial epidemiology; Case-crossover study
摘要：
Background: Positive associations between ambient PM2.5 and cardiorespiratory disease have been well demonstrated during the past decade. However, few studies have examined the adverse effects of PM2.5 based on an entire population of a megalopolis. In addition, most studies in China have used averaged data, which results in variations between monitoring and personal exposure values, creating an inherent and unavoidable type of measurement error.
Methods: This study was conducted in Wuhan, a megacity in central China with about 10.9 million people. Daily hospital admission records, from October 2016 to December 2018, were obtained from the Wuhan Information center of Health and Family Planning, which administrates all hospitals in Wuhan. Daily air pollution concentrations and weather variables in Wuhan during the study period were collected. We developed a land use regression model (LUR) to assess individual PM2.5 exposure. Time-stratified case-crossover design and conditional logistic regression models were adopted to estimate cardiorespiratory hospitalization risks associated with short-term exposure to PM2.5. We also conducted stratification analyses by age, sex, and season.
Results: A total of 2,806,115 hospital admissions records were collected during the study period, from which we identified 332,090 cardiovascular disease admissions and 159,365 respiratory disease admissions. Short-term exposure to PM2.5 was associated with an increased risk of a cardiorespiratory hospital admission. A 10 mug/m(3) increase in PM2.5 (lag0-2 days) was associated with an increase in hospital admissions of 1.23% (95% CI 1.01-1.45%) and 1.95% (95% CI 1.63-2.27%) for cardiovascular and respiratory diseases, respectively. The elderly were at higher PM-induced risk. The associations appeared to be more evident in the cold season than in the warm season.
Conclusions: This study contributes evidence of short-term effects of PM2.5 on cardiorespiratory hospital admissions, which may be helpful for air pollution control and disease prevention in Wuhan.
合写作者：
Jingling Liao,Haomin Yang,Jingdong Suo,Xiaodie Wang,Kuizhuang Jiao,Dieyi Chen,Tianyu Liu,Xingyuan Liu
论文类型：
期刊论文
通讯作者：
Lu Ma
学科门类：
医学
一级学科：
公共卫生与预防医学
文献类型：
J
卷号：
22
期号：
1
页面范围：
128
字数：
5505
ISSN号：
1465-993X (Electronic)
是否译文：
否
发表时间：
2021-04-30
收录刊物：
SCI
发表时间：
2021-04-30
学科：
流行病与卫生统计学
所在单位：公共卫生学院