Feng Yong
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Personal Information
- Supervisor of Master's Candidates
- Name (Pinyin):Feng Yong
- E-Mail:
- Education Level:研究生毕业
- Business Address:基础医学院1号楼
- Gender:Male
- Contact Information:18627962533； yongfeng@whu.edu.cn
- Teacher College:School of Basic Medical Science
- Discipline:
Pathogenic Organisms;
Microbiology
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IFN-λs inhibit Hantaan virus infection through the JAK-STAT pathway and expression of Mx2 protein
- Date of Publication:2019-06-26
- Hits:
Journal:
Genes & ImmunityAbstract:
Hantaan virus (HTNV), member of the newly defined Hantaviridae family, within the order Bunyavirales, can cause a hemorrhagic fever with renal syndrome with high fatality rates in humans. However, no specific antiviral agents are currently available for HTNV infection approved by the US Food and Drug Administration. Although interferon lambdas (IFN-λs) have been shown to induce an antiviral state against HTNV, the molecular mechanisms remain to be determined. In this study, we found that IFN-λs exerted its anti-HTNV effect by activating Janus kinase/signal transducers andIndexed by:
Journal paperCorrespondence Author:
Hou Wei,Feng YongDiscipline:
MedicineFirst-Level Discipline:
Basic MedicineVolume:
20Issue:
3Page Number:
234-244Translation or Not:
noDate of Publication:
2019-03-01Included Journals:
SCILinks to published journals:
https://www.nature.com/articles/s41435-018-0028-x