Feng Yong
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Personal Information
- Supervisor of Master's Candidates
- Name (Pinyin):Feng Yong
- E-Mail:
- Education Level:研究生毕业
- Business Address:基础医学院1号楼
- Gender:Male
- Contact Information:18627962533； yongfeng@whu.edu.cn
- Teacher College:School of Basic Medical Science
- Discipline:
Pathogenic Organisms;
Microbiology
Other Contact Information
- ZipCode:
- PostalAddress:
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- Telephone:
- email:
Expression of HIV-encoded microRNA-TAR and its inhibitory effect on viral replication in human primary macrophages
- Date of Publication:2019-06-26
- Hits:
Journal:
Archives of VirologyFunded by:
NSFC81271818, NSFC81471940Abstract:
A number of virus-encoded microRNAs have been shown to play important roles in virus replication and virus-host interactions, although the expression and function of miR-TAR-3p derived from the human immunodeficiency virus type 1 (HIV-1) TAR element remain controversial. In this study, miR-TAR-3p was detected in human peripheral blood monocyte-derived macrophages (MDMs) infected by HIV-1. Overexpression of miR-TAR-3p impaired viral replication, while inhibition of miR-TAR-3p enhanced it. Additionally, miR-TAR-3p repressed viral transcription and replication by targeting the TAR element in theIndexed by:
Journal paperDiscipline:
MedicineFirst-Level Discipline:
Basic MedicineVolume:
161Issue:
5Page Number:
1115–1123Translation or Not:
noDate of Publication:
2016-05-26Included Journals:
SCILinks to published journals:
https://link.springer.com/article/10.1007%2Fs00705-016-2755-5