标题：
Gaseous pollutant exposure affects semen quality in central China: a cross-sectional study
点击次数：
影响因子：
4.5
DOI码：
10.1111/andr.12655
发表刊物：
Andrology
关键字：
cross-sectional study; gaseous pollutants; NO2; semen quality; SO2
摘要：
Background: Limited studies have explored the association between gaseous pollutant exposures and male reproductive outcomes, and findings remained inconsistent. Objectives: To evaluate the potential association between gaseous pollutants and semen quality within different exposure windows.
Materials and Methods: We adopted semen quality data of 1852 subjects who attended the Reproductive Medicine Center of Renmin Hospital at Wuhan University during January 1st, 2013, to August 3rd, 2015. A generalized linear model was employed to assess the relationship between each exposure variable and sperm parameters in different exposure windows. Results SO2 exposure with lag 0-90 days was significantly associated with decreased sperm concentration (beta: -1.362; 95% CI: -1.844, -0.879), sperm count (beta: -2.979; 95% CI: -4.267, -1.691), and PR (beta: -0.551; 95% CI: -0.710, -0.393). Similar trends were observed for SO2 exposure with three other key periods (lag 0-9, 10-14, and 70-90 days). NO2 exposure with lag 0-90 days was also associated with decreased sperm concentration (beta: -0.517; 95% CI: -1.006, -0.027), sperm count (beta: -1.914; 95% CI: -3.214, -0.615), and PR (beta: -0.264; 95% CI: -0.425, -0.102). No relationship between gaseous pollutant exposure and ejaculate volume was observed in any exposure window.
Discussion and Conclusion: Our study indicated a strong adverse effect of gaseous pollutants on semen quality outcomes during the sperm development. Gaseous pollution exposure appeared to be more detrimental in the initial phase of spermatogenesis.
合写作者：
Tian, X,Ye, B
论文类型：
期刊论文
通讯作者：
Ma, L
学科门类：
医学
一级学科：
公共卫生与预防医学
文献类型：
J
卷号：
8
期号：
1
页面范围：
117-124
字数：
5018
ISSN号：
2047-2927
是否译文：
否
发表时间：
2019-06-07
收录刊物：
SCI
发表时间：
2019-06-07
学科：
流行病与卫生统计学
所在单位：公共卫生学院