标题：
Short-Term Effects of Carbonaceous Components in PM2.5 on Pulmonary Function: A Panel Study of 37 Chinese Healthy Adults
点击次数：
影响因子：
4.614
DOI码：
10.3390/ijerph16132259
发表刊物：
International Journal of Environmental Research and Public Health
刊物所在地：
Switzerland
项目来源：
General Project of Hubei Provincial Health and Family Planning Commission (Project No. WJ2017M008)
关键字：
carbonaceous componentsfine; particulate matter; healthy adults; respiratory function; mixed-effect model
摘要：
Objectives: To explore the health effects of indoor/outdoor carbonaceous compositions in PM2.5 on pulmonary function among healthy students living in the local university campus.
Methods: Daily peak expiratory flow (PEF) and forced expiratory volume in 1 second (FEV1) were measured among 37 healthy students in the morning and evening for four two-week periods. Concurrent concentrations of indoor and outdoor PM2.5 (particulate matter with an aerodynamic diameter <= 2.5 mu m), carbonaceous components in PM2.5, ambient temperature, and relative humidity in the study area were also obtained. Mixed-effects model was applied to evaluate the associations between carbonaceous components and lung function. Different lags for the carbonaceous components were investigated.
Results: In single-pollutant model, a 10 mu g/m(3) increase of indoor and outdoor EC (elemental carbon) associated with -3.93 (95%CI: -6.89, -0.97) L/min and -3.21 (95%CI: -5.67, -0.75) L/min change in evening PEF at lag 0 day, respectively. Also, a 10 mu g/m(3) increase of indoor and outdoor POC (primary organic carbon) concentration was significantly associated with -5.82 (95%CI: -10.82, -0.81) L/min and -7.32 (95%CI: -12.93, -1.71) L/min change of evening PEF at lag 0 day. After adjusting total mass of PM2.5, indoor EC consistently had a significant adverse impact on evening PEF and FEV1 at lag3 day and a cumulative effect at lag0-3 day.
Conclusions: This study suggests that carbonaceous components in PM2.5 indeed have impacts on pulmonary function among healthy young adults especially on evening PEF. Thus, the local mitigation strategies on pollution are needed.
合写作者：
Zuo, Shanshan,Feng, Huan
论文类型：
期刊论文
通讯作者：
Ma, Lu
学科门类：
医学
一级学科：
公共卫生与预防医学
文献类型：
J
卷号：
16
期号：
13
字数：
7628
ISSN号：
1660-4601
是否译文：
否
发表时间：
2019-06-30
收录刊物：
SCI、SSCI
发表时间：
2019-06-30
学科：
流行病与卫生统计学
所在单位：公共卫生学院